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Axon 2767
CAS [326914-10-7]
MF C22H27ClN4O2MW 414.93
SU11652 is a sunitinib-like RTK inhibitor of PDGFR-β, VEGFR2, FGFR1 and FLT3, with IC50 values of 3, 27, 170 and 1.5 nM, respectively. Moreover, SU11652 inhibits cKit, acid sphingomyelinase, destabilizes lysosomes, and inhibits multidrug resistance.
KEYWORDS: SU11652 | supplier | RTK inhibitor | SU 11652 | SU-11652 | CAS [326914-10-7] | SCF-PDGF-VEGF | c-KIT | PDGFR | VEGFR | FLT3 | Inhibitor | Receptors | Acid sphingomyelinase
(Z)-5-((5-chloro-2-oxoindolin-3-ylidene)methyl)-N-(2-(diethylamino)ethyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide
[326914-10-7]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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