SMURF1 inhibitor A01 - A01

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 2426

CAS [1007647-73-5]

MF C22H20ClF3N4O3S
MW 512.93

  • Purity: 99%
  • Soluble in DMSO

SMURF1 inhibitor A01


SMAD ubiquitination regulatory factor-1 (SMURF1) E3 ubiquitin-protein ligase inhibitor (Kd value 3.7 nM), that strongly inhibits Smad1/5 ubiquitination under rhBMP-2 stimulation. A01 enhances BMP signaling responsiveness in C2C12 cells, and potentiates BMP-2 induced osteoblastic activity.
Size Unit Price Stock
10 mg €115.00 In Stock
50 mg €460.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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