Tenovin 6 - Tnv 6

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 2249

CAS [1011557-82-6]

MF C25H34N4O2S
MW 454.63

  • Purity: 99%
  • Soluble in 0.1N HCl(aq) and DMSO

Tenovin 6


Small molecule, water soluble p53 activator and SIRT inhibitor (IC50 values of 21 μM, 10 μM, and 67 μM for purified human SIRT1, 2, and 3, respectively, in a peptide deacetylase assay). Tenovin 6 reduces chronic lymphocytic leukaemia (CLL) cell viability with dysregulation of autophagy, without increasing p53-pathway activity. It induces p53-dependent apoptosis in many malignant cells.
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5 mg €105.00 In Stock
25 mg €365.00 In Stock
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2 x 5 mg €160.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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