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Axon 1662
CAS [252003-65-9]
MF C20H24BrF2N5O3SMW 532.40
A potent and oral tyrosine kinase inhibitor (TKI), targeting VEGFR2 and basic FGF kinases (IC50 to be 11 and 9 nM respectively); selective relative to EGFR, PDGF-ß, and other related TKs; inhibits VEGF-stimulated autophosphorylation of VEGFR2 in a whole cell assay with an IC50 value of 6 nM.
KEYWORDS: CP 547632 | supplier | VEGFR2 inhibitor | CP547632 | CP-547632 | CAS [252003-65-9] | VEGF | VEGFR | VEGFR2 | Inhibitor | Receptors
3-(4-bromo-2,6-difluorobenzyloxy)-5-(3-(4-(pyrrolidin-1-yl)butyl)ureido)isothiazole-4-carboxamide
[252003-65-9]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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