SB 431542

Based on 413 publications in PubMed 10 10 413

Axon 1661

CAS [301836-41-9]

MF C22H16N4O3
MW 384.39

  • Purity: 99%
  • Soluble in DMSO

SB 431542

Description

Potent and selective inhibitor of TGF-β1 superfamily activin receptor-like kinase (ALK), specifically at ALK5 (IC50: 94 nM) and its relatives ALK4 (IC50: 140 nM) and ALK7; SB431542 inhibits endogenous activin and TGF-β signaling, but has no effect on BMP signaling; a useful tool for studing the role of TGF-β, activin and many cellular processes.

*Promotion: SB 431542 is also part of Inhibitor Set(s):

Axon 5004 Axon 5005 Axon 5007
Axon 5009


KEYWORDS: SB 431542 | supplier | ALK5 inhibitor | SB431542 | CAS [301836-41-9] | TGF-β1 | TGF-beta | RSTK | activin receptor-like kinase | BMP signaling | Transforming Growth Factor | osteosarcoma

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Size Unit Price Stock
5 mg €70.00 In Stock
10 mg €95.00 In Stock
50 mg €320.00 In Stock
Special Offers
Size Unit Price Stock
2 x 10 mg €140.00 In Stock
2 x 50 mg €460.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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