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Featured Products
Axon 1661
CAS [301836-41-9]
MF C22H16N4O3MW 384.39
Potent and selective inhibitor of TGF-β1 superfamily activin receptor-like kinase (ALK), specifically at ALK5 (IC50: 94 nM) and its relatives ALK4 (IC50: 140 nM) and ALK7; SB431542 inhibits endogenous activin and TGF-β signaling, but has no effect on BMP signaling; a useful tool for studing the role of TGF-β, activin and many cellular processes.
*Promotion: SB 431542 is also part of Inhibitor Set(s):
KEYWORDS: SB 431542 | supplier | ALK5 inhibitor | SB431542 | CAS [301836-41-9] | TGF-β1 | TGF-beta | RSTK | activin receptor-like kinase | BMP signaling | Transforming Growth Factor | osteosarcoma
List of publications using SB 431542 (Axon 1661) purchased from Axon Medchem
4-(4-(benzo[d][1,3]dioxol-5-yl)-5-(pyridin-2-yl)-1H-imidazol-2-yl)benzamide
[301836-41-9]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!