Your cart

There are no items in your shopping cart

HLI 373

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1643

CAS [1782531-99-0]

MF C18H23N5O2.2HCl
MW 414.33

  • Purity: 98%
  • Soluble in water and DMSO

HLI 373

Description

A water soluble and potent Hdm2 inhibitor that inhibits the ubiquitin ligase activity of Hdm2, stabilizes p53 and activates p53-dependent transcription, and induces cell death; HLI 373 is effective in inducing apoptosis of several tumor cells lines that are sensitive to DNA-damaging agents
Order
Size Unit Price Stock
5 mg €100.00 In Stock
25 mg €360.00 In Stock
Need more? Bulk Inquiry

Related Products

Axon ID Name Description From price
1129 BI 2536 PLK1 inhibitor €60.00
1131 GW 843682X PLK1 and PLK3 inhibitor €85.00
1473 BI 6727 PLK1 Inhibitor €90.00
1530 RO 3306 CDK1 inhibitor €80.00
1585 Nutlin-3 MDM2 inhibitor (p53 specific) €95.00
1597 Aurora A inhibitor I Aurora A inhibitor €125.00
1625 GSK579289A PLK1 Inhibitor €110.00
1626 GSK 461364 analogue II PLK1 Inhibitor €130.00
1630 Aurora A inhibitor II Aurora A inhibitor €125.00
1688 GSK 461364 PLK1 inhibitor €105.00
1880 Nutlin-3a Inhibitor of MDM2 €95.00
1881 Nutlin-3b Less potent (+)-enantiomer of Nutlin-3 €90.00
1904 SMER 3 Inhibitor of an SCF family E3 Ubiquitin ligase €90.00
1910 MLN0905 PLK1 inhibitor €95.00
1953 PRT 4165 E3 Ubiquitin ligase Bmi1/Ring1A inhibitor €70.00
1961 MK 5108 Inhibitor of Aurora A kinase €110.00
2003 MLN8237 Second generation selective Aurora A inhibitor €90.00
2008 Tenovin 1 Activates p53 through inhibition of SIRT 1 and 2 €70.00
2009 RITA Activates p53 through inhibition of MDM2 €105.00
2164 SJ 172550 Small molecule inhibitor of MDMX €95.00
2249 Tenovin 6 Small water soluble p53 activator and SIRT inhibitor €105.00
2437 SP 141 Specific MDM2 inhibitor with therapeutic effects in breast cancer models €120.00
1538 JNJ 26854165 HDM2 inhibitor €105.00
1586 JNJ 26854165 dihydrochloride HDM2 inhibitor €105.00
2565 N106 Activator of E1 ligase mediated SERCA2a SUMOylation €95.00
2639 AMG 232 Potent, selective, and orally bioavailable MDM2-p53 inhibitor €120.00
2645 CC-885 Cereblon (CRBN) modulator with potent anti-tumour activity €130.00
2741 SAR405838 MDM2-p53 inhibitor €125.00
2939 JTP 0819958 Selective linear ubiquitin chain assembly complex (LUBAC) inhibitor €125.00
2984 WS-383 Highly potent, selective, and cellular active inhibitor of DCN1-UBC12 protein-protein interaction €125.00
3737 Siremadlin Potent, selective, and orally bioavailable MDM2-p53 inhibitor €130.00
3751 NVP-CGM097 Inhibitor of MDM2 Inquire
3752 NVP-CGM097 dihydrochloride Inhibitor of MDM2 Inquire
3765 DS-3032 Orally available, potent and selective inhibitor of the p53-MDM2 interaction Inquire
4035 RG-7388 Potent and selective MDM2 antagonist Inquire

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

Newsletter
Give Feedback
 
Send E-mail

Customer Support

About Axon Medchem

Download Product Catalog

Download the Axon Ligands™ catalogue 2021 Spring Edition

Follow Us

© 2016 Axon Medchem. All Rights Reserved.

Send us a message

×

Contact Us

* Required Fields

Please wait...