Ruxolitinib - INCB 018424 phosphate

Based on 620 publications in PubMed 10 10 620

Axon 1598

CAS [1092939-17-7]

MF C17H18N6.H3O4P
MW 404.36

  • Purity: 99%
  • Optical purity: 98% ee
  • Soluble in water and DMSO

Ruxolitinib

Description

An orally bioavailable, potent and selective inhibitor of Janus-associated kinase (JAK) 1 and 2, with IC50 to be 2.7, 4.5 and 332 nM for JAK1, JAK2 and JAK3 respectively; selectivity >100 fold for a wide range of other kinases. It acts by blocking the JAK/STAT pathway
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2 mg €80.00 In Stock
5 mg €105.00 In Stock
25 mg €365.00 In Stock
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2 x 5 mg €160.00 In Stock
2 x 25 mg €560.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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