Order

Size
Price
Stock
Qty

Stattic

Axon 2314
CAS:  19983-44-9
Purity:  99%
  • Soluble in DMSO
  • MF:  C8H5NO4S
  • MW:  211.19

Description

The first nonpeptidic small-molecule inhibitor of STAT3 activation, dimerization, and nuclear translocation (IC50 value 5.1 μM for inhibition of the binding of a phosphotyrosine-containing peptide derived from the gp130 receptor to the STAT3 SH2 domain). Stattic demonstrates good selectivity for STAT3 inhibition over STAT1, and increases the apoptotic rate of STAT3-dependent breast cancer cell lines.

More Information

Certificate of Analysis

Material Safety Data Sheet

Parent CAS No. 19983-44-9
Chemical Name 6-nitroBenzo[b]thiophene-1,1-dioxide
SMILES C12=CC([N+]([O-])=O)=CC=C1C=CS2(=O)=O
MFCD MFCD00173799
InChi InChI=1S/C8H5NO4S/c10-9(11)7-2-1-6-3-4-14(12,13)8(6)5-7/h1-5H
InChiKey ZRRGOUHITGRLBA-UHFFFAOYSA-N
CID 2779853
Short Description STAT3 inhibitor

Related Products

AXON ID NAME FROM PRICE
1338 CP 690550

From $66.00

1378 AG 490

From $71.50

1588 TG 101348

From $88.00

1598 Ruxolitinib

From $71.50

1681 Momelotinib

From $88.00

1778 AZ 960

From $104.50

1843 JAK2 inhibitor 13

From $121.00

1955 Baricitinib

From $77.00

1992 AS 1517499

From $143.00

2072 Tofacitinib citrate

From $126.50

2217 PF 956980

From $99.00

2219 AT 9283

From $99.00

2231 XL 019

From $110.00

2313 S3I 201

From $99.00

2316 WP 1066

From $104.50

2324 SC 144 hydrochloride

From $143.00

2489 Brassinin

From $82.50

2517 Napabucasin

From $115.50

2539 Solcitinib

From $99.00

2554 LY 2784544

From $104.50

3786 BP-1-102

From $99.00

3834 Alantolactone

From $99.00

Loading...