BMS-911543
- Soluble in DMSO
- MF: C23H28N8O
- MW: 432.52
Description
BMS-911543 is a potent, selective and orally active inhibitor of JAK2 (Ki = 0.48 nM), highly selective over JAK1 (Ki = 1117 nM) and JAK3 (Ki = 357 nM).
More Information
| Parent CAS No. | 1271022-90-2 |
|---|---|
| Chemical Name | N,N-dicyclopropyl-4-(1,5-dimethyl-1H-pyrazol-3-ylamino)-6-ethyl-1-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide |
| extra_info | Sold in collaboration with Chemietek |
| SMILES | C12C=C(C(N(C3CC3)C3CC3)=O)N(CC)C=1N=C(NC1=NN(C)C(C)=C1)C1N=CN(C)C=12 |
| MFCD | N.A. |
| InChi | InChI=1S/C23H28N8O/c1-5-30-17(23(32)31(14-6-7-14)15-8-9-15)11-16-20-19(24-12-28(20)3)21(26-22(16)30)25-18-10-13(2)29(4)27-18/h10-12,14-15H,5-9H2,1-4H3,(H,25,26,27) |
| InChiKey | JCINBYQJBYJGDM-UHFFFAOYSA-N |
| CID | 50922691 |
| Short Description | JAK2 inhibitor |
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