NS 11394

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1457

CAS [951650-22-9]

MF C23H19N3O
MW 353.42

  • Purity: 99%
  • Soluble in DMSO

NS 11394


A unique subtype-selective GABAA receptor positive allosteric modulator (PAM); with a subtype selectivity profile at GABAA receptors of α5 > α3 > α2 > α1. Compared with other subtype-selective ligands, NS11394 is unique in having superior efficacy at GABAA-α3 receptors while maintaining low efficacy at GABAA-α1 receptors, which might be attributed for its significantly reduced side effect profile in rat.

KEYWORDS: NS 11394 | supplier | 951650-22-9 | GABAA PAM | NS11394 | GABA-A | γ-aminobutyric acid | gamma-aminobutyric acid | positive allosteric modulator | agonist

Size Unit Price Stock
5 mg €110.00 In Stock
25 mg €330.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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