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Apigenin
- LY080400
- Soluble in 0.1N NaOH(aq) and DMSO
- MF: C15H10O5
- MW: 270.24
Description
Apigenin is a natural plant flavonoid and selective CK2 inhibitor that targets CK2-dependent signaling pathways. Moreover, Apigenin has been reported to inhibit protein kinase C activity and mitogen activated protein kinase (MAPK).
More Information
| Parent CAS No. | 520-36-5 |
|---|---|
| Chemical Name | 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one |
| SMILES | C1(O)C=C2OC(C3C=CC(O)=CC=3)=CC(=O)C2=C(O)C=1 |
| MFCD | MFCD00006831 |
| InChi | InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-7,16-18H |
| InChiKey | KZNIFHPLKGYRTM-UHFFFAOYSA-N |
| CID | 5280443 |
| Short Description | CK2 inhibitor |
References
- N Nelson et al. Apigenin: Selective CK2 inhibitor increases Ikaros expression and improves T cell homeostasis and function in murine pancreatic cancer. PLoS One. 2017 Feb 2;12(2):e0170197.
- D Patel et al. Apigenin and cancer chemoprevention: progress, potential and promise (review). Int J Oncol. 2007 Jan;30(1):233-45.
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