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Longdaysin
- Soluble in DMSO
- MF: C16H16F3N5
- MW: 335.33
Description
Longdaysin is a potent inhibitor of protein kinases CK1δ, CK1α, ERK2, and CDK7 with IC50 values of 8.8, 5.6, 52, and 29 µM, respectively. Furthermore, Longdaysin is a small molecule that potently lengthens the circadian period in a dose-dependent manner.
More Information
| Parent CAS No. | 1353867-91-0 |
|---|---|
| Chemical Name | 9-Isopropyl-N-(3-(trifluoromethyl)benzyl)-9H-purin-6-amine |
| SMILES | C12N=CN(C(C)C)C=1N=CN=C2NCC1C=CC=C(C(F)(F)F)C=1 |
| MFCD | MFCD20527323 |
| InChi | InChI=1S/C16H16F3N5/c1-10(2)24-9-23-13-14(21-8-22-15(13)24)20-7-11-4-3-5-12(6-11)16(17,18)19/h3-6,8-10H,7H2,1-2H3,(H,20,21,22) |
| InChiKey | REKSFCCYDQMSIN-UHFFFAOYSA-N |
| CID | 49830252 |
| Short Description | CK1δ/CK1α inhibitor |
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