Bulk Inquiry
CX 4945 hydrochloride
- Silmitasertib hydrochloride
Axon 1965
- Parent CAS: 1009820-21-6
Purity:
98%
- Soluble in 0.1N NaOH(aq) and DMSO
- MF: C19H12ClN3O2.HCl
- MW: 386.23
Description
Orally available, potent and selective casein kinase 2 (CK2) inhibitor
More Information
| Parent CAS No. | 1009820-21-6 |
|---|---|
| Chemical Name | 5-(3-chlorophenylamino)benzo[c][2,6]naphthyridine-8-carboxylic acid hydrochloride |
| SMILES | C1(NC2=CC=CC(Cl)=C2)C2=C(C=NC=C2)C2=CC=C(C(O)=O)C=C2N=1.Cl |
| MFCD | MFCD13184796 |
| InChi | InChI=1S/C19H12ClN3O2.ClH/c20-12-2-1-3-13(9-12)22-18-15-6-7-21-10-16(15)14-5-4-11(19(24)25)8-17(14)23-18;/h1-10H,(H,22,23)(H,24,25);1H |
| InChiKey | OBOIGMDUOMSAHW-UHFFFAOYSA-N |
| CID | 86346660 |
| Short Description | CK2 inhibitor |
References
- A Siddiqui-Jain et al. CX-4945, an Orally Bioavailable Selective Inhibitor of Protein Kinase CK2, Inhibits Prosurvival and Angiogenic Signaling and Exhibits Antitumor Efficacy. Cancer Res. 2010, 70, 10288-10298.
- AD Ferguson et al. Structural basis of CX-4945 binding to human protein kinase CK2. FEBS Lett. 2011, 585(1), 104-110.
- F Pierre et al. Pre-clinical characterization of CX-4945, a potent and selective small molecule inhibitor of CK2 for the treatment of cancer. Mol. Cell Biochem. 2011, 356(1-2), 37-43.
Related Products
| AXON ID | NAME | FROM PRICE |
|---|---|---|
| 1792 | PF 4800567 |
From $121.00 |
| 1854 | TTP 22 |
From $115.50 |
| 2202 | CK2 inhibitor 10 |
From $115.50 |
| 2297 | LH 846 |
From $104.50 |
| 2547 | SR 3029 |
From $148.50 |
| 2717 | Apigenin |
From $77.00 |
| 2998 | Longdaysin |
From $137.50 |
| 3279 | CKI-7 dihydrochloride |
From $132.00 |
| 4329 | Etimizol |
From $143.00 |
| 4330 | Didesmethyletimizol |
From $187.00 |
| 4331 | Desmethyletimizol |
From $198.00 |
| 4371 | SJ3149 |
From $154.00 |
Other Categories
Get a Quote for
Loading...