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N-Desmethyltamoxifen hydrochloride

Axon 3986
  • Parent CAS:  31750-48-8
Purity:  99%
  • Soluble in DMSO and EtOH
  • MF:  C25H28ClNO
  • MW:  393.95

Description

N-Desmethyltamoxifen is the major free metabolite of Tamoxifen (Axon 3252) in human serum. Also, N‑Desmethyltamoxifen is a protein kinase C inhibitor with an IC50 value of 8 μM.

More Information

Parent CAS No. 31750-48-8
Chemical Name (Z)-2-(4-(1,2-Diphenylbut-1-enyl)phenoxy)-N-methylethanamine hydrochloride
SMILES C(=C(/C1C=CC=CC=1)CC)(/C1C=CC(OCCNC)=CC=1)C1C=CC=CC=1.Cl
MFCD N.A.
InChi InChI=1S/C25H27NO.ClH/c1-3-24(20-10-6-4-7-11-20)25(21-12-8-5-9-13-21)22-14-16-23(17-15-22)27-19-18-26-2;/h4-17,26H,3,18-19H2,1-2H3;1H/b25-24-;
InChiKey GMLHJWZEYLTNJW-BJFQDICYSA-N
CID 24200424
Short Description Tamoxifen metabolite

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