Your cart

There are no items in your shopping cart

Stem Cell Alternative 2i inhibitor Set

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 2130

CAS [N.A.]

MF N.A.
MW N.A.

  • Purity: 99%
  • Soluble in DMSO

Stem Cell Alternative 2i inhibitor Set

Description

A convenient set of SRC inhibitor CGP 77675 (Axon 2097) and GSK-3 inhibitor CHIR99021 (Axon 1386); an alternative 2i inhibitor set vs the conventional 2i inhibitor set (Axon 2128) of MEK inhibitor PD 0325901 and GSK3 inhibitor CHIR99021.

The dual inhibition of Src and GSK-3 signaling by CGP 77675 and CHIR99021 (termed alternative 2i) was found to maintain mouse embryonic stem cell (mESC) self-renewal and pluripotency marker expression as efficiently as the dual inhibition of MAPK and GSK-3 by PD 0325901 and CHIR99021 (conventional 2i, Axon 2128). This alternative 2i method provides a versatile tool not only for the maintenance of mESCs in serum-free conditions but also for the derivation of ESCs from mouse embryos.

Read more: Additional Product Information

Show all Axon Ligand™ Sets

Order
Size Unit Price Stock
Each 2 mg €110.00 In Stock
Each 5 mg €160.00 In Stock
Need more? Bulk Inquiry

Related Products

Axon ID Name Description From price
1386 CHIR99021 GSK-3 inhibitor €60.00
2097 CGP 77675 Src Family kinase (SFK) inhibitor €65.00
2128 Stem Cell 2i inhibitor Set Set of MEK inhibitor PD0325901 (Axon 1408) and GSK-3 inhibitor CHIR99021 (Axon 1386) €90.00
2129 Stem Cell 3i inhibitor Set Set of FGFR inhibitor SU5402 (Axon 1667), MEK inhibitor PD184352 (Axon 1368) and GSK-3 inhibitor CHIR99021 (Axon 1386) €130.00
5009 Stem Cell 4i inhibitor Set Set of Thiazovivin, SB 431542, PD0325901, and CHIR99021 (inhibitors of ROCK, TGF-β, MEK, and GSK-3 resp.) €170.00
2366 NG 25 trihydrochloride Type II inhibitor of TAK1 (MAP3K7) and MAP4K2 (GCK) €75.00
2381 WH-4-023 Orally active src-family selective lck inhibitor €90.00
2778 Squarunkin A Selective UNC119–cargo interaction inhibitor €125.00
3153 BRD5648 Negative control compound of BRD0705 as a GSK3α inhibitor €210.00
3154 rac-BRD0705 GSK3α inhibitor €140.00
2931 BRD0705 First-in-class, paralog selective GSK3α inhibitor €210.00
3284 Saracatinib Inhibitor of SRC and ABL tyrosine kinases €70.00
3099 TL02-59 Potent, selective and orally active Fgr and Lyn inhibitor €120.00
3579 Tideglusib GSK-3 inhibitor €60.00
3973 XL-228 Multitargeted protein kinase inhibitor (IGF1R, Aurora,FGFR, ABL,ALK and SRC) Inquire
3936 Bisindolylmaleimide I Potent and selective PKC inhibitor €120.00
4010 BLK degrader compound 9 First potent and highly selective monomeric degrader of B-lymphoid tyrosine kinase (BLK)  Recently added €180.00

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

Newsletter
Give Feedback
 
Send E-mail

Customer Support

About Axon Medchem

Download Product Catalog

Download the Axon Ligands™ catalogue 2021 Spring Edition

Follow Us

© 2016 Axon Medchem. All Rights Reserved.

Send us a message

×

Contact Us

* Required Fields

Please wait...