More About Stem Cells
Special attention is offered to the class of Axon Ligands™ that finds its application (among other applications in most cases) in stem cell research projects. The medical use of stem cells, cells with the ability to perpetuate themselves through self-renewal and to differentiate into a particular cell type through differentiation, is receiving extensive interest as they might regenerate damaged tissue under the right conditions[1]. This unique capacity could serve patients suffering from organ malfunction, cell deficiency, and/or neurodegenerative diseases such as Alzheimer’s and Parkinson’s disease by replacing affected/deficient cells with healthy new cells[2]. We have selected several combinations of Axon Ligands™ that have been used frequently as a combined set for epigenetic research. These sets include, for example inhibitors of GSK3, FGFR, MEK, SRC, etc.
Compound libraries of Axon Ligands™ can generally be offered with bulk discount . All Axon Ligands™ in the libraries are individually identified and analyzed to meet the strong requirements to pass our QC for drug standards.
[1] Stem cells, cancer, and cancer stem cells. Tannishtha Reya, Sean J. Morrison, Michael F. Clarke, Irving L. Weissman. Nature, Vol 414, 2001, 105.
[2] Embryonic stem cells in drug discovery. J. McNeish. Nature Rev. Drug Disc. 2004, 3, 70.