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Featured Products
Axon 1491
CAS [700874-72-2]
MF C22H19N5OMW 369.42
Orally active transforming growth factor β receptor (TGF-βR) kinase inhibitor under clinical development; IC50 values to be 86 nm (TβR1) and 2 nM (TβR2) respectively.
KEYWORDS: LY 2157299 | supplier | TGF-βR2 inhibitor | Galunisertib | LY2157299 | LY-2157299 | CAS [700874-72-2] | TGF-beta | transforming growth factor | TβR1 | TβR2 | antagonist | non-small cell lung cancer | NSCLC | Smad | pSmad
List of publications using LY 2157299 (Axon 1491) purchased from Axon Medchem
4-[2-(6-Methyl-pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-quinoline-6-carboxylic acid amide
[700874-72-2]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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