List of publications using LY 2157299 (Axon 1491) purchased from Axon Medchem

(total 20 publications; updated on AUGUST-2017)

2017
Jeibmann, A., Schulz, J., Eikmeier, K., Johann, P. D., Thiel, K., Tegeder, I., ... & Paulus, W. (2017). SMAD dependent signaling plays a detrimental role in a fly model of SMARCB1-deficiency and the biology of atypical teratoid/rhabdoid tumors. Journal of neuro-oncology, 131(3), 477-484.
 
2016
Schweinlin, M., Wilhelm, S., Schwedhelm, I., Hansmann, J., Rietscher, R., Jurowich, C., ... & Metzger, M. (2016). Development of an advanced primary human in vitro model of the small intestine. Tissue Engineering Part C: Methods, 22(9), 873-883.
 
Montorsi, L., Parenti, S., Losi, L., Ferrarini, F., Gemelli, C., Rossi, A., ... & Zanocco-Marani, T. (2016). Expression of μ-protocadherin is negatively regulated by the activation of the β-catenin signaling pathway in normal and cancer colorectal enterocytes. Cell death & disease, 7(6), e2263.
 
Kawai, T., Yasuchika, K., Seo, S., Higashi, T., Ishii, T., Miyauchi, Y., ... & Ogiso, S. (2016). Identification of keratin19-positive cancer stem cells associating human hepatocellular carcinoma using 18F-fluorodeoxyglucose positron emission tomography. Clinical Cancer Research, clincanres-0871.
 
Calderón-Gómez, E., Bassolas-Molina, H., Mora-Buch, R., Dotti, I., Planell, N., Esteller, M., ... & Ordás, I. (2016). Commensal-specific CD4+ cells from patients with Crohn’s disease have a T-helper 17 inflammatory profile. Gastroenterology, 151(3), 489-500.
 
Schweinlin, M. O. (2016). Development of advanced human intestinal in vitro models.
 
2015
Lin, C., Rezaee, F., Waasdorp, M., Shi, K., van der Poll, T., Borensztajn, K., & Spek, C. A. (2015). Protease activated receptor-1 regulates macrophage-mediated cellular senescence: a risk for idiopathic pulmonary fibrosis. Oncotarget, 6(34), 35304.
(SB431542 and LY2157299 from Axon Medchem)
 
Adkins, C. E., Nounou, M. I., Mittapalli, R. K., Terrell-Hall, T. B., Mohammad, A. S., Jagannathan, R., & Lockman, P. R. (2015). A novel preclinical method to quantitatively evaluate early-stage metastatic events at the murine blood–brain barrier. Cancer Prevention Research, 8(1), 68-76.

Keratin 19, a cancer stem cell marker in human hepatocellular carcinoma.
Kawai, T., Yasuchika, K., Ishii, T., Katayama, H., Yoshitoshi, E. Y., Ogiso, S., ... & Uemoto, S. (2015). 
Clin Cancer Res. 2015 Mar 27. [Epub ahead of print]

A Novel Preclinical Method to Quantitatively Evaluate Early-Stage Metastatic Events at the Murine Blood–Brain Barrier.
Adkins, C. E., Nounou, M. I., Mittapalli, R. K., Terrell-Hall, T. B., Mohammad, A. S., Jagannathan, R., & Lockman, P. R. (2015).
Cancer Prev Res (Phila). 2015 Jan;8(1):68-76.

COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING OSTEOARTHRITIS.
Cao, Xu.
U.S. Patent No. 20,150,139,909. 21 May 2015.

2014
Benzalkonium Chloride Induces Subconjunctival Fibrosis Through the COX-2–Modulated Activation of a TGF-β1/Smad3 Signaling Pathway.
Huang, C., Wang, H., Pan, J., Zhou, D., Chen, W., Li, W., ... & Liu, Z. (2014).
Invest Ophthalmol Vis Sci. 2014 Nov 18;55(12):8111-22.

Protease‐activated receptor 2 suppresses lymphangiogenesis and subsequent lymph node metastasis in a murine pancreatic cancer model. 
Shi, K., Queiroz, K., Roelofs, J. J., van Noesel, C. J., Richel, D. J., & Spek, C. A. (2014).
J Pathol. 2014 Nov;234(3):398-409. 

Targeted Therapy Sensitivity and Resistance in Solid Malignancies.
Jokinen, E. (2014). 
PhD thesis. University of Oulu.
*LY2157299, SD208, XAV939 and DBZ from Axon Medchem have been used in this study. 

2013
Programmed cell senescence during mammalian embryonic development. 
Muñoz-Espín, D., Cañamero, M., Maraver, A., Gómez-López, G., Contreras, J., Murillo-Cuesta, S., ... & Serrano, M. (2013).
Cell. 2013 Nov 21;155(5):1104-18.  
*LY2157299 from Axon Medchem has been used in this study. 

Glucocorticoids alleviate intestinal ER stress by enhancing protein folding and degradation of misfolded proteins. 
Das, I., Png, C. W., Oancea, I., Hasnain, S. Z., Lourie, R., Proctor, M., ... & McGuckin, M. A. (2013).
J Exp Med. 2013 Jun 3;210(6):1201-16.  

2012 and earlier
Costimulatory protein 4IgB7H3 drives the malignant phenotype of glioblastoma by mediating immune escape and invasiveness.
Lemke, D., Pfenning, P. N., Sahm, F., Klein, A. C., Kempf, T., Warnken, U., ... & Wick, W. (2012). 
Clinical Cancer Research, 18(1), 105-117.

Costimulatory protein 4IgB7H3 drives the malignant phenotype of glioblastoma by mediating immune escape and invasiveness.
Lemke, D., Pfenning, P. N., Sahm, F., Klein, A. C., Kempf, T., Warnken, U., ... & Wick, W. (2012).
Clin Cancer Res. 2012 Jan 1;18(1):105-17. 

Cardiac treatment using anti-fibrotic agents.
Dudley, S. C., & Sutliff, R. L. (2011).
U.S. Patent Application 13/091,972. US 20110262398 A1.

Nodal/Activin signaling drives self-renewal and tumorigenicity of pancreatic cancer stem cells and provides a target for combined drug therapy.
Lonardo, E., Hermann, P. C., Mueller, M. T., Huber, S., Balic, A., Miranda-Lorenzo, I., ... & Heeschen, C. (2011).
Cell Stem Cell, 9(5), 433-446.

(This is an incomplete list, updated in AUGUST-2017) 

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