LDN 212854 trihydrochloride

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 2201

CAS [2109414-80-2]

MF C25H22N6.3HCl
MW 515.87

  • Purity: 99%
  • Soluble in water and DMSO

LDN 212854 trihydrochloride

Description

Potent ALK2-biased BMP type I receptor kinase inhibitor (IC50 values 2.4 nM, 1.3 nM, and 85.8 nM for ALK1, 2, and 3 resp.), showing nearly 4 orders of selectivity for BMP versus the closely related TGF-β and Activin type I receptors. Closely related to LDN 193189 (Axon 1509).

KEYWORDS: LDN 212854 trihydrochloride | supplier | BMP inhibitor | LDN212854 | LDN-212854 | CAS [2109414-80-2] | [1432597-26-6] | TGF-β | BMP-ALK | ALK | type I | dorsomorphin | ALK2 | ALK-2 | ALK1 | ALK3 | bone morphogenetic protein | Antagonist | Receptors

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5 mg €105.00 In Stock
25 mg €360.00 In Stock
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2 x 5 mg €160.00 In Stock
2 x 25 mg €520.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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