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SB4
- Soluble in DMSO and EtOH
- MF: C14H10BrNOS
- MW: 320.2
Description
SB4 is a potent BMP agonist with an EC50 value of 74 nM. Activation of BMP signaling by SB4 increased the phosphorylation of key second messengers (SMAD-1/5/9) and also increased expression of direct target genes (inhibitors of DNA binding, Id1 and Id3) in canonical BMP signaling.
More Information
| Parent CAS No. | 100874-08-6 |
|---|---|
| Chemical Name | 2-(4-Bromobenzylthio)benzo[d]oxazole |
| MFCD | MFCD01603921 |
| Short Description | BMP agonist |
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