PITCOIN3
- Soluble in DMSO
- MF: C26H23N7O4S3
- MW: 593.7
Description
PITCOIN3 is a potent, highly selective and cell-permeable inhibitor of phosphatidylinositol 3-kinase C2α (PI3KC2α) with an IC50 value of 126 nM.
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More Information
| Parent CAS No. | 2397679-88-6 |
|---|---|
| Chemical Name | N-(4-(3-(Methylsulfonamido)phenyl)thiazol-2-yl)-2-(4-oxo-3-phenethyl-3,4-dihydropteridin-2-ylthio)acetamide |
| SMILES | C1N=C2C(=O)N(CCC3C=CC=CC=3)C(SCC(NC3=NC(C4C=C(NS(C)(=O)=O)C=CC=4)=CS3)=O)=NC2=NC=1 |
| MFCD | N.A. |
| InChi | InChI=1S/C26H23N7O4S3/c1-40(36,37)32-19-9-5-8-18(14-19)20-15-38-25(29-20)30-21(34)16-39-26-31-23-22(27-11-12-28-23)24(35)33(26)13-10-17-6-3-2-4-7-17/h2-9,11-12,14-15,32H,10,13,16H2,1H3,(H,29,30,34) |
| InChiKey | ZQUVBPXCXCKORU-UHFFFAOYSA-N |
| CID | 146269130 |
| Short Description | PI3KC2α inhibitor |
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