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AZD6482
- KIN-193
- Optical Purity: Optically pure
- Soluble in DMSO
- MF: C22H24N4O4
- MW: 408.45
Description
AZD6482 is a potent and selective inhibitor of the p110β isoform of PI3K with an IC50 value of 0.69 nM. In addition, AZD6482 can inhibit the growth of tumors driven by p110β or PTEN-loss in vivo.
More Information
| Parent CAS No. | 1173900-33-8 |
|---|---|
| Chemical Name | (R)-2-(1-(7-Methyl-2-morpholino-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl)ethylamino)benzoic acid |
| SMILES | C1(C(O)=O)C(N[C@@H](C2=CC(C)=CN3C(=O)C=C(N4CCOCC4)N=C23)C)=CC=CC=1 |&1:6,r| |
| MFCD | N.A. |
| InChi | InChI=1S/C22H24N4O4/c1-14-11-17(15(2)23-18-6-4-3-5-16(18)22(28)29)21-24-19(12-20(27)26(21)13-14)25-7-9-30-10-8-25/h3-6,11-13,15,23H,7-10H2,1-2H3,(H,28,29)/t15-/m1/s1 |
| InChiKey | IRTDIKMSKMREGO-OAHLLOKOSA-N |
| CID | 44137675 |
| Short Description | PI3K p110β inhibitor |
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