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Axon 2543
CAS [1998197-39-9]
MF C21H18N2O2SMW 362.44
Brain penetrant cannabinoid CB1 receptor positive allosteric modulator (PAM) which augments the in vitro and in vivo pharmacological actions of the CB1 orthosteric agonists CP55940 (pEC50 value 6.90) and N-arachidonoylethanolamine (AEA) and reduces neuropathic pain in the mouse with no psychoactive effects.
KEYWORDS: ZCZ 011 | supplier | PAM of CB1 | ZCZ011 | CAS [1998197-39-9] | Cannabinoids | CB1 | PAM | positive allosteric modulator | brain penetrant | neuropathic pain
6-methyl-3-(2-nitro-1-(thiophen-2-yl)ethyl)-2-phenyl-1H-indole
[1998197-39-9]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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