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Solcitinib
- GSK 2586184 - GLPG 0778
- Soluble in DMSO
- MF: C22H23N5O2
- MW: 389.45
Description
Selective JAK1 inhibitor originally developed for the treatment of systemic lupus erythematosus, psoriasis and ulcerative colitis.
More Information
| Parent CAS No. | 1206163-45-2 |
|---|---|
| Chemical Name | N-(5-(4-(3,3-dimethylazetidine-1-carbonyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide |
| SMILES | C1(C(NC2N=C3N(N=2)C(C2=CC=C(C(N4CC(C)(C)C4)=O)C=C2)=CC=C3)=O)CC1 |
| MFCD | N.A. |
| InChi | InChI=1S/C22H23N5O2/c1-22(2)12-26(13-22)20(29)16-10-6-14(7-11-16)17-4-3-5-18-23-21(25-27(17)18)24-19(28)15-8-9-15/h3-7,10-11,15H,8-9,12-13H2,1-2H3,(H,24,25,28) |
| InChiKey | MPYACSQFXVMWNO-UHFFFAOYSA-N |
| CID | 44603362 |
| Short Description | JAK1 inhibitor |
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