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ML 351

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 2312

CAS [847163-28-4]

MF C15H11N3O
MW 249.27

  • Purity: 98%
  • Soluble in DMSO

ML 351

Description

Potent and selective inhibitor of 12/15-lipoxygenase (IC50 value 200 nM against human 12/15-LOX) with >250-fold selectivity versus related LOX isozymes. ML351 is protective against oxidative glutamate toxicity in mouse neuronal HT22 cells and does not reduce the active-site ferric ion. ML 351 significantly reduced infarct size following permanent focal ischemia in a mouse model of ischemic stroke
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Size Unit Price Stock
5 mg €125.00 In Stock
25 mg €425.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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