AT 9283

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 2219

CAS [896466-04-9]

MF C19H23N7O2
MW 381.43

  • Purity: 99%
  • Soluble in water and DMSO

AT 9283


A multitargeted kinase inhibitor with high affinity for Aurora A and B, JAK2/3, and BCR-Abl(T315I) (IC50 values 3, 3, 1.2, 1.1, and 4 nM respectively). AT 9283 has a potent anti-proliferative activity in a panel of Ba/F3 and human cell lines expressing the BCR-Abl fusion protein or its mutant forms including T315I, and it has the potential to significantly benefit patients with imatinib-resistant CML or with Ph+ ALL.
Size Unit Price Stock
5 mg €85.00 In Stock
25 mg €295.00 In Stock
Special Offers
Size Unit Price Stock
2 x 5 mg €130.00 In Stock
2 x 25 mg €480.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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