Order

Size
Price
Stock
Qty

Special Offers

Size
Price
Stock
Qty

CK2 inhibitor 10

Axon 2202
CAS:  1361229-76-6
Purity:  99%
  • Soluble in DMSO
  • MF:  C18H14N2O4S
  • MW:  354.38

Description

Potent and ATP-competitive inhibitor of protein kinase (CK2; IC50 values of 32 nM and 46 nM for CK2α and CK2α' respectively). At 0.30 μM, compound 10 exhibited a >50% inhibitory effect against 9 out of 70 other kinases besides CK2α and CK2α′, while at 30 nM >75% inhibition was observed for two other kinases (DYRK1B and FLT3) only. It exhibited potent cytotoxicity towards lung cancer cells A549, colorectal cancer cells HCT-116, and breast cancer cells MCF-7.

More Information

Parent CAS No. 1361229-76-6
Chemical Name 4-(2-(4-methoxybenzamido)thiazol-5-yl)benzoic acid
SMILES C(O)(=O)C1=CC=C(C2SC(NC(=O)C3=CC=C(OC)C=C3)=NC=2)C=C1
MFCD N.A.
InChi InChI=1S/C18H14N2O4S/c1-24-14-8-6-12(7-9-14)16(21)20-18-19-10-15(25-18)11-2-4-13(5-3-11)17(22)23/h2-10H,1H3,(H,22,23)(H,19,20,21)
InChiKey UPIVZLFKYMNZDG-UHFFFAOYSA-N
CID 57342036
Short Description CK2 inhibitor

Related Products

AXON ID NAME FROM PRICE
1792 PF 4800567

From $121.00

1854 TTP 22

From $115.50

1965 CX 4945 hydrochloride

From $99.00

2297 LH 846

From $104.50

2547 SR 3029

From $148.50

2717 Apigenin

From $77.00

2970 GSK626616

From $132.00

2998 Longdaysin

From $137.50

3279 CKI-7 dihydrochloride

From $132.00

3538 INDY

From $121.00

3540 ProINDY

From $121.00

4056 DYRK1A inhibitor compound 11

From $165.00

4329 Etimizol

From $143.00

4330 Didesmethyletimizol

From $187.00

4331 Desmethyletimizol

From $198.00

4371 SJ3149

From $154.00

Loading...