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GSK626616
Axon 2970
CAS:
1025821-33-3
Purity:
99%
- Soluble in DMSO
- MF: C18H10Cl2N4OS
- MW: 401.27
Description
GSK626616 is a potent, orally bioavailable inhibitor of DYRK3 with an IC50 value of 0.7 nM. GSK626616 inhibits other members of the DYRK family, e.g., DYRK1A and DYRK2, with similar potency and with an approximate 20-fold selectivity versus the next most potently inhibited kinase, casein kinase 2.
More Information
| Parent CAS No. | 1025821-33-3 |
|---|---|
| Chemical Name | (5Z)-2-(2,6-dichlorophenylimino)-5-(quinoxalin-6-ylmethylene)thiazolidin-4-one |
| SMILES | C1(/C=C2SC(NC3C(Cl)=CC=CC=3Cl)=NC2=O)C=C2N=CC=NC2=CC=1 |
| MFCD | N.A. |
| InChi | InChI=1S/C18H10Cl2N4OS/c19-11-2-1-3-12(20)16(11)23-18-24-17(25)15(26-18)9-10-4-5-13-14(8-10)22-7-6-21-13/h1-9H,(H,23,24,25)/b15-9- |
| InChiKey | RJPNRXFBYZVRIB-DHDCSXOGSA-N |
| CID | 135416229 |
| Short Description | DYRK3 inhibitor |
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