DG2 - S6K1 Inhibitor DG2

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1903

CAS [871340-88-4]

MF C16H17BrN6O
MW 389.25

Purity: 99%
Soluble in DMSO

DG2

Description

Potent and selective inhibitor of p70 ribosomal S6 kinase 1 (S6K1) (IC50: 9.1 nM for S6K1); no Akt activity (IC50: 22000 nM); ATP-competitive and cell-permeable

T Okuzumi et al. Inhibitor Hijacking of Akt Activation. Nat. Chem. Biol. 2009, 5(7), 484–493.

BT Wang et al. The mammalian target of rapamycin regulates cholesterol biosynthetic gene expression and exhibits a rapamycin-resistant transcriptional profile. PNAS 2011, 108 (37), 15201-15206.

RSK inhibitor (p70 ribosomal S6 kinase 1 specific)

Chemical name

3-bromo-4-(4-(2-methoxyphenyl)piperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine

Parent CAS No.

[871340-88-4]

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10 mg	€95.00	In Stock
50 mg	€350.00	In Stock

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DG2 - S6K1 Inhibitor DG2

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DG2 - S6K1 Inhibitor DG2

Description

Chemical name

Parent CAS No.

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