Obatoclax
- GX15-070
- Soluble in DMSO
- MF: C20H19N3O
- MW: 317.38
Description
Obatoclax is an orally bioavailable inhibitor of B-cell lymphoma-2 (BCL-2) family proteins.
More Information
| Parent CAS No. | 803712-67-6 |
|---|---|
| Chemical Name | 2-(2-((3,5-dimethyl-1H-pyrrol-2-yl)methylene)-3-methoxy-2H-pyrrol-5-yl)-1H-indole |
| extra_info | Sold in collaboration with Chemietek |
| MFCD | N.A. |
| Short Description | BCL2 inhibitor |
References
- M. Konopleva et al. Mechanisms of Antileukemic Activity of the Novel Bcl-2 Homology Domain-3 Mimetic GX15-070 (Obatoclax) Cancer Research 2008; 68.
- SA Parikh et al. A Multicenter Phase I/II Study of Obatoclax Mesylate Administered as a 3- or 24-Hour Infusion in Older Patients with Previously Untreated Acute Myeloid Leukemia Clinical Lymphoma, Myeloma & Leukemia 2010; 10.
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