Bulk Inquiry
BI-6C9
- Soluble in DMSO
- MF: C23H25N3O4S2
- MW: 471.59
Description
BI-6C9 is an inhibitor of BID, a member of the BH3-only proteins. BI-6C9 is an antiapoptotic molecule targeting Bcl-2 as shown by the ability to inhibit tBID-induced SMAC release, caspase-3 activation, and cell death. BI-6C9 reduces proapoptotic activity of BID in vitro and in cells.
More Information
| Parent CAS No. | 791835-21-7 |
|---|---|
| Chemical Name | N-(4-(4-Aminophenylthio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide |
| SMILES | C1C=C(SC2C=CC(NC(=O)CCCNS(C3C=CC(OC)=CC=3)(=O)=O)=CC=2)C=CC=1N |
| MFCD | N.A. |
| InChi | InChI=1S/C23H25N3O4S2/c1-30-19-8-14-22(15-9-19)32(28,29)25-16-2-3-23(27)26-18-6-12-21(13-7-18)31-20-10-4-17(24)5-11-20/h4-15,25H,2-3,16,24H2,1H3,(H,26,27) |
| InChiKey | LCFUJBSKPDPGKO-UHFFFAOYSA-N |
| CID | 11547341 |
| Short Description | BID inhibitor |
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