Bulk Inquiry
WEHI-9625
- Soluble in DMSO
- MF: C34H27NO5S2
- MW: 593.71
Description
WEHI-9625 is a first-in-class, potent, and selective mBAK-mediated apoptosis inhibitor (EC50 value of 69 nM) which binds to VDAC2. In contrast to caspase inhibitors, WEHI-9625 blocks apoptosis before mitochondrial damage, preserving cellular function and long-term clonogenic potential.
More Information
| Parent CAS No. | N.A. |
|---|---|
| Chemical Name | 7-[2-(4-Methoxybenzoyl)phenyl]-N-[(4-methylphenyl)methyl]-5,5-dioxo-4H-thieno[3,2-c]thiochromene-2-carboxamide |
| SMILES | C1C=C(C2C=CC3C4SC(C(NCC5C=CC(C)=CC=5)=O)=CC=4CS(=O)(=O)C=3C=2)C(C(C2C=CC(OC)=CC=2)=O)=CC=1 |
| MFCD | N.A. |
| InChi | InChI=1S/C34H27NO5S2/c1-21-7-9-22(10-8-21)19-35-34(37)30-17-25-20-42(38,39)31-18-24(13-16-29(31)33(25)41-30)27-5-3-4-6-28(27)32(36)23-11-14-26(40-2)15-12-23/h3-18H,19-20H2,1-2H3,(H,35,37) |
| InChiKey | DQVRUUKJUZNKSW-UHFFFAOYSA-N |
| CID | 138805616 |
| Short Description | Apoptosis inhibitor |
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