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BTSA1
Axon 3431
CAS:
314761-14-3
Purity:
99%
- Soluble in DMSO
- MF: C21H14N6OS2
- MW: 430.51
Description
BTSA1 is a potent BAX activator with an IC50 value of 250 nM and an EC50 value of 144 nM. BTSA1-induced BAX activation effectively and selectively promotes apoptosis of acute myeloid leukemia cells.
More Information
| Parent CAS No. | 314761-14-3 |
|---|---|
| Chemical Name | (Z)-3-Phenyl-1-(4-phenylthiazol-2-yl)-4-(2-(thiazol-2-yl)hydrazono)-1H-pyrazol-5(4H)-one |
| SMILES | C1(C2C=CC=CC=2)/C(=N/NC2=NC=CS2)/C(=O)N(C2SC=C(C3C=CC=CC=3)N=2)N=1 |
| MFCD | N.A. |
| InChi | InChI=1S/C21H14N6OS2/c28-19-18(24-25-20-22-11-12-29-20)17(15-9-5-2-6-10-15)26-27(19)21-23-16(13-30-21)14-7-3-1-4-8-14/h1-13H,(H,22,25)/b24-18- |
| InChiKey | KYVZVVOQWWCVPP-MOHJPFBDSA-N |
| CID | 3857348 |
| Short Description | BAX activator |
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