AZD2014
- Vistusertib
- Optical Purity: Optically pure
- Soluble in DMSO
- MF: C25H30N6O3
- MW: 462.54
Description
AZD2014 is a potent and orally bioavailable dual mTORC1/mTORC2 inhibitor with IC50 at lower nM, demonstrating on-target in vitro and in vivo activities in experimental models.
More Information
| Parent CAS No. | 1009298-59-2 |
|---|---|
| Chemical Name | 3-(2,5-bis((S)-3-Methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-N-methylbenzamide |
| extra_info | Sold in collaboration with Chemietek |
| SMILES | C1C(N2[C@@H](C)COCC2)=C2C=NC(N3[C@@H](C)COCC3)=NC2=NC=1C1C=CC=C(C(=O)NC)C=1 |&1:3,14,r| |
| MFCD | N.A. |
| InChi | InChI=1S/C25H30N6O3/c1-16-14-33-9-7-30(16)22-12-21(18-5-4-6-19(11-18)24(32)26-3)28-23-20(22)13-27-25(29-23)31-8-10-34-15-17(31)2/h4-6,11-13,16-17H,7-10,14-15H2,1-3H3,(H,26,32)/t16-,17-/m0/s1 |
| InChiKey | AASISPHNIRSVAV-IRXDYDNUSA-N |
| CID | 169488015 |
| Short Description | mTORC1/mTORC2 inhibitor |
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