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(RS)-AMPA hydrobromide
- Parent CAS: 77521-29-0
- Soluble in water, DMSO and EtOH
- MF: C7H10N2O4·HBr
- MW: 267.08
Description
AMPA hydrobromide, a bioisostere of glutamic acid, is a highly selective AMPA receptor agonist. The free zwitterionic form AMPA (Axon 3415) is also available.
More Information
| Parent CAS No. | 77521-29-0 |
|---|---|
| Chemical Name | 2-Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propanoic acid hydrobromide |
| SMILES | O1C(C)=C(CC(N)C(O)=O)C(O)=N1.Br |
| MFCD | MFCD00055183 |
| InChi | InChI=1S/C7H10N2O4.BrH/c1-3-4(6(10)9-13-3)2-5(8)7(11)12;/h5H,2,8H2,1H3,(H,9,10)(H,11,12);1H |
| InChiKey | KUAHVIUZGLGASU-UHFFFAOYSA-N |
| CID | 11957558 |
| Short Description | AMPA agonist |
References
- T Honoré et al. The binding of [3H]AMPA, a structural analogue of glutamic acid, to rat brain membranes. J Neurochem. 1982 Jan;38(1):173-8.
- H Bräuner-Osborne et al. A new highly selective metabotropic excitatory amino acid agonist: 2-amino-4-(3-hydroxy-5-methylisoxazol-4-yl)butyric acid. J Med Chem. 1996 Aug 2;39(16):3188-94.
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