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Azithromycin
- CP 62993 - Zithromax
- Parent CAS: 83905-01-5
- Optical Purity: Optically pure
- Soluble in DMSO
- MF: C38H72N2O12
- MW: 748.98
Description
Azithromycin is a macrolide antibiotic and bacterial protein synthesis inhibitor. It binds the 50S ribosomal subunit and interferes with translation, thereby suppressing bacterial growth.
Macrolide antibiotics are widely used to study ribosomal translation inhibition and antibacterial susceptibility. Azithromycin is pharmacologically relevant for bacterial protein synthesis research, antimicrobial testing and host-pathogen infection models.
Key Features
- Macrolide antibiotic
- Inhibits bacterial protein synthesis
- Targets the 50S ribosomal subunit
- Relevant to antibacterial susceptibility studies
Applications
- Bacterial translation assays
- Antimicrobial susceptibility testing
- Host-pathogen infection models
- Macrolide mechanism-of-action research
More Information
| Parent CAS No. | 83905-01-5 |
|---|---|
| Chemical Name | (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)-2-ethyl-3,4,10-trihydroxy-13-((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yloxy)-3,5,6,8,10,12,14-heptamethy... |
| extra_info | . |
| SMILES | [C@@]1([H])(O[C@H](C)C[C@H](N(C)C)[C@H]1O)O[C@H]1[C@](C)(O)C[C@@H](C)CN(C)[C@H](C)[C@H]([C@](C)(O)[C@@H](CC)OC(=O)[C@H](C)[C@@H](O[C@]2([H])O[C@@H](C)[C@@H]([C@](C)(OC)C2)O)[C@@H]1C)O |&1:0,3,6,10,13,14,18,23,25,26,29,35,37,39,42,44,45,51,r| |
| MFCD | N.A. |
| InChi | InChI=1S/C38H72N2O12/c1-15-27-38(10,46)31(42)24(6)40(13)19-20(2)17-36(8,45)33(52-35-29(41)26(39(11)12)16-21(3)48-35)22(4)30(23(5)34(44)50-27)51-28-18-37(9,47-14)32(43)25(7)49-28/h20-33,35,41-43,45-46H,15-19H2,1-14H3/t20-,21-,22+,23-,24-,25+,26+,27-,28+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1 |
| InChiKey | MQTOSJVFKKJCRP-BICOPXKESA-N |
| CID | 447043 |
| Short Description | Antibiotic |
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