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Clarithromycin
- A56268 - TE031
Axon 3445
CAS:
81103-11-9
- Optical Purity: Optically pure
- Soluble in DMSO and EtOH
- MF: C38H69NO13
- MW: 747.95
Description
Clarithromycin is an acid-stable orally administered macrolide antimicrobial drug, which has a broad spectrum of antimicrobial activity. The antibacterial effect of clarithromycin has been attributed to reversible binding to the 50S ribosomal subunit within the bacterial cell, thus inhibiting translocation of aminoacyl transfer-RNA and consequent protein synthesis.
More Information
| Parent CAS No. | 81103-11-9 |
|---|---|
| Chemical Name | (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)-14-ethyl-12,13-dihydroxy-4-((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yloxy)-7-methoxy-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione |
| SMILES | C1(=O)[C@H](C)C[C@@](C)(OC)[C@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@@H](C)[C@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@@H](C)C(=O)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@H]1C |&1:2,5,9,11,13,16,20,22,24,26,28,32,34,37,42,45,48,50,r| |
| MFCD | N.A. |
| InChi | InChI=1S/C38H69NO13/c1-15-26-38(10,45)31(42)21(4)28(40)19(2)17-37(9,47-14)33(52-35-29(41)25(39(11)12)16-20(3)48-35)22(5)30(23(6)34(44)50-26)51-27-18-36(8,46-13)32(43)24(7)49-27/h19-27,29-33,35,41-43,45H,15-18H2,1-14H3/t19-,20-,21+,22+,23-,24+,25+,26-,27+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1 |
| InChiKey | AGOYDEPGAOXOCK-KCBOHYOISA-N |
| CID | 84029 |
| Short Description | Antibiotic |
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