Varenicline tartrate - Chantix | Champix | CP 526555-18

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 2074

CAS [375815-87-5]

MF C13H13N3.C4H6O6
MW 361.35

Purity: 100%
Optical purity: Optically pure
Soluble in water and DMSO

Varenicline tartrate

Description

Selective α4β2 nicotinic acetylcholine receptor (nAChR) partial agonist; Smoking cessation drug. Available also another drug form, Varenicline di-HCl (Axon 1384).

D.E. Jorenby et al. Efficacy of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs placebo or sustained-release bupropion for smoking cessation: a randomized controlled trial. JAMA 2006, 296, 56-63.

R.S. Obach et al. Metabolism and disposition of varenicline, a selective alpha4beta2 acetylcholine receptor partial agonist, in vivo and in vitro. Drug Metab. Dispos. 2006, 34, 121-30.

K.B. Mihalak et al. Varenicline is a partial agonist at alpha4beta2 and a full agonist at alpha7 neuronal nicotinic receptors. Mol. Pharmacol. 2006, 70, 801-805.

Selective α4β2 nicotinic acetylcholine receptor (nAChR) partial agonist

Chemical name

7,8,9,10-tetrahydro-6,10-methano-6H-pyrazino(2,3-h)(3)benzazepine tartrate

Parent CAS No.

[249296-44-4]

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Size	Unit Price	Stock
10 mg	€90.00	In Stock
50 mg	€290.00	In Stock

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Varenicline tartrate - Chantix | Champix | CP 526555-18

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Varenicline tartrate - Chantix | Champix | CP 526555-18

Description

Chemical name

Parent CAS No.

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