AT 1001

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 2401

CAS [1314801-63-2]

MF C15H21BrN2
MW 309.24

  • Purity: 100%
  • Optical purity: Relative stereochemistry
  • Soluble in 0.1N HCl(aq) and DMSO

AT 1001


High affinity and selective α3β4 nAChR ligand (Ki value 2.6 nM at α3β4 nAChR) with both partial agonistic and antagonistic effects, and >90-fold selective over the other major subtypes, the α4β2 and α7 nAChR. AT-1001 potently and dose-dependently blocks nicotine self-administration in rats, without affecting food responding, and shows a mechanism of action very different from varenicline (Axon 1384 (HCl salt) and Axon 2074 (tartrate salt)).

Size Unit Price Stock
10 mg €95.00 In Stock
50 mg €295.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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