AT 1001

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 2401

CAS [1314801-63-2]

MF C15H21BrN2
MW 309.24

  • Purity: 100%
  • Optical purity: Relative stereochemistry
  • Soluble in 0.1N HCl(aq) and DMSO

AT 1001

Description

High affinity and selective α3β4 nAChR ligand (Ki value 2.6 nM at α3β4 nAChR) with both partial agonistic and antagonistic effects, and >90-fold selective over the other major subtypes, the α4β2 and α7 nAChR. AT-1001 potently and dose-dependently blocks nicotine self-administration in rats, without affecting food responding, and shows a mechanism of action very different from varenicline (Axon 1384 (HCl salt) and Axon 2074 (tartrate salt)).

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10 mg €95.00 In Stock
50 mg €295.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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