PNU 282987 hydrochloride

Based on 140 reference(s) in Google Scholar 8 10 140

Axon 2908

CAS [123464-89-1]

MF C14H18Cl2N2O
MW 301.21

  • Purity: 99%
  • Optical purity: Optically pure
  • Soluble in water and DMSO
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PNU 282987 hydrochloride

Description

PNU 282987 hydrochloride is an α7 nicotinic acetylcholine receptor (nAChR) agonist with Ki (α7 nAChR) and EC50 (α7-5HT3 chimera) values of 27 nm and 154 nM, respectively. PNU 282987 hydrochloride was also shown to open native α7 nAChRs in cultured rat neurons and to reverse an amphetamine-induced gating deficit in rats.

KEYWORDS: PNU 282987 hydrochloride | supplier | nAChR agonist | PNU282987 hydrochloride | PNU-282987 hydrochloride | CAS [123464-89-1] | [711085-63-1] | Acetylcholine | nAChR | Agonist | Ion Channels | Schizophrenia

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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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