Varenicline dihydrochloride - Chantix | Champix

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1384

CAS [866823-63-4]

MF C13H13N3.2HCl
MW 284.18

Purity: 99%
Soluble in water

Varenicline dihydrochloride

Description

Selective α4β2 nicotinic acetylcholine receptor partial agonist; Smoking cessation drug. Available also another drug form, Varenicline tartrate (Axon 2074).

DE Jorenby et al. Efficacy of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs placebo or sustained-release bupropion for smoking cessation: a randomized controlled trial. JAMA 2006, 296 (1), 56–63.

RS Obach et al. Metabolism and disposition of varenicline, a selective alpha4beta2 acetylcholine receptor partial agonist, in vivo and in vitro. Drug Metab Dispos 2006, 34, 121-30.

Mihalak K.B. et al. Varenicline is a partial agonist at alpha4beta2 and a full agonist at alpha7 neuronal nicotinic receptors. Mol Pharmacol. 2006 Sep;70(3):801-805.

Nicotinic acetylcholine receptor agonist

Chemical name

7,8,9,10-tetrahydro-6,10-methano-6H-pyrazino(2,3-h)(3)benzazepine dihydrochloride

Parent CAS No.

[249296-44-4]

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Size	Unit Price	Stock
10 mg	€80.00	In Stock
50 mg	€200.00	In Stock

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Varenicline dihydrochloride - Chantix | Champix

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Description

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