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Axon 2694
CAS [360791-49-7]
MF C18H17BrN2O2SMW 405.31
4BP-TQS is an allosteric agonist of α7 nicotinic acetylcholine receptors (nAChR). The agonism was shown to act through a site topographically distinct from the ACh site. 4BP-TQS was a more potent and efficacious agonist of α7 nAChR than ACh (8-fold lower EC50 and 45-fold larger maximal response).
The bioactive enantiomer of 4BP-TQS, GAT107 (Axon 2621), is also available.
KEYWORDS: 4BP-TQS | supplier | α7 nAChR allosteric agonist | 4BPTQS | 4-BPTQS | 4-BP-TQS | CAS [360791-49-7] | Acetylcholine | nAChR | Allosteric agonist | Ion Channels | CAS [1476053-27-6]
4-(4-Bromophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide
[360791-49-7]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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