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Axon 2621
CAS [1476807-74-5]
MF C18H17BrN2O2SMW 405.31
GAT107, the bioactive enantiomer of 4BP-TQS (Axon 2694), is an allosteric agonist (EC50 value 28 μM) and positive allosteric modulator (PAM) of α7 nicotinic acetylcholine receptors. GAT107 reverses nociception in mouse models of inflammatory and neuropathic pain.
KEYWORDS: GAT107 | supplier | α7 nAChR agonist and PAM | GAT-107 | GAT 107 | CAS [1476807-74-5] | Acetylcholine | nAChR | Allosteric agonist | Ion Channels
(3aR,4S,9bS)-4-(4-bromophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide
[1476807-74-5]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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