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PHA 543613 dihydrochloride
- Parent CAS: 478149-53-0
- Optical Purity: Optically pure
- Soluble in water and DMSO
- MF: C15H17N3O2.2HCl
- MW: 344.24
Description
More Information
| Parent CAS No. | 478149-53-0 |
|---|---|
| Chemical Name | (R)-N-(quinuclidin-3-yl)furo[2,3-c]pyridine-5-carboxamide dihydrochloride |
| extra_info | . |
| SMILES | Cl.Cl.C12OC=CC=1C=C(C(N[C@@H]1C3CCN(CC3)C1)=O)N=C2 |&1:11,r| |
| MFCD | N.A. |
| InChi | InChI=1S/C15H17N3O2.2ClH/c19-15(12-7-11-3-6-20-14(11)8-16-12)17-13-9-18-4-1-10(13)2-5-18;;/h3,6-8,10,13H,1-2,4-5,9H2,(H,17,19);2*1H/t13-;;/m0../s1 |
| InChiKey | USJDQOUQSDDWPO-GXKRWWSZSA-N |
| CID | 11493927 |
| Short Description | nAChR agonist |
References
- DG Wishka et al. Discovery of N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide, an agonist of the alpha7 nicotinic acetylcholine receptor, for the potential treatment of cognitive (...). J. Med. Chem. 2006, 49(14), 4425-4436.
- PR Krafft et al. PHA-543613 Preserves Blood–Brain Barrier Integrity After Intracerebral Hemorrhage in Mice. Stroke, 2013, 44(6), 1743-1747.
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