|
2639
|
AMG 232
|
Potent, selective, and orally bioavailable MDM2-p53 inhibitor |
€120.00
|
|
3763
|
CFT-7455
|
Orally active monofunctional degrader for IKZF1/3 |
Inquire
|
|
2935
|
COH000
|
First-in-class, highly specific, covalent allosteric inhibitor of SUMO E1 |
€175.00
|
|
3709
|
DKM 2-93
|
Selective inhibitor of UBA5 |
€70.00
|
|
1643
|
HLI 373
|
HDM2 inhibitor |
€100.00
|
|
3064
|
HOIPIN 11a
|
Selective, cell-permeable and covalent inhibitor of RBR E3 ubiquitin ligase HOIP |
€180.00
|
|
2972
|
HOIPIN-8
|
Potent linear ubiquitin chain assembly complex (LUBAC) inhibitor |
€130.00
|
|
1538
|
JNJ 26854165
|
HDM2 inhibitor |
€105.00
|
|
1586
|
JNJ 26854165 dihydrochloride
|
HDM2 inhibitor |
€105.00
|
|
2939
|
JTP 0819958
|
Selective linear ubiquitin chain assembly complex (LUBAC) inhibitor |
€125.00
|
|
2947
|
JTP 1048196
|
Prodrug of JTP 0819958; LUBAC inhibitor |
€125.00
|
|
3109
|
ML-792
|
Potent and selective inhibitor of SUMO-activating enzyme (SAE) |
€145.00
|
|
3829
|
MLN7243
|
Cell permeable small molecule inhibitor targeting ubiquitin-activating enzymes (UAE, also known as E1 enzymes) |
Inquire
|
|
2565
|
N106
|
Activator of E1 ligase mediated SERCA2a SUMOylation |
€95.00
|
|
1585
|
Nutlin-3
|
MDM2 inhibitor (p53 specific) |
€95.00
|
|
1880
|
Nutlin-3a
|
Inhibitor of MDM2 |
€95.00
|
|
1881
|
Nutlin-3b
|
Less potent (+)-enantiomer of Nutlin-3 |
€90.00
|
|
3751
|
NVP-CGM097
|
Inhibitor of MDM2 |
Inquire
|
|
3752
|
NVP-CGM097 dihydrochloride
|
Inhibitor of MDM2 |
Inquire
|
|
1953
|
PRT 4165
|
E3 Ubiquitin ligase Bmi1/Ring1A inhibitor |
€70.00
|
|
4035
|
RG-7388
|
Potent and selective MDM2 antagonist |
Inquire
|
|
2009
|
RITA
|
Activates p53 through inhibition of MDM2 |
€105.00
|
|
2741
|
SAR405838
|
MDM2-p53 inhibitor |
€125.00
|
|
3737
|
Siremadlin
|
Potent, selective, and orally bioavailable MDM2-p53 inhibitor |
€130.00
|
|
2164
|
SJ 172550
|
Small molecule inhibitor of MDMX |
€95.00
|
|
1904
|
SMER 3
|
Inhibitor of an SCF family E3 Ubiquitin ligase |
€90.00
|
|
2426
|
SMURF1 inhibitor A01
|
Inhibitor of E3 ubiquitin-protein ligase SMURF1 |
€115.00
|
|
2437
|
SP 141
|
Specific MDM2 inhibitor with therapeutic effects in breast cancer models |
€120.00
|
|
2894
|
STF 62247
|
Inducer of apoptosis and autophagy in VHL-deficient RCC cells |
€85.00
|
|
3797
|
TAK-981 oxalate
|
Inhibitor of SUMOylation |
€110.00
|