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Enzymes

Items 1 to 30 of 1267 total

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Axon ID Name Description From price
1066 N-Cyclopropyl-N-methyl-2-aminotetraline hydrobromide MAO inhibitor €95.00
3144 (+)-Blebbistatin Negative control of (±)-Blebbistatin as an inhibitor of class II myosins €90.00
1730 (+)-Kifunensine α-mannosidase inhibitor €120.00
3074 (-)-Blebbistatin Selective inhibitor of class II myosins; Active enantiomer of (±)-Blebbistatin €90.00
3759 (aR)-RP-6306 (aR)-enantiomer of RP-6306 (Axon 3668); PKMYT1 inhibitor €180.00
1229 (R)-(-)-Rolipram PDE4 inhibitor €110.00
3743 (R)-HTS-3 hydrochloride First potent, selective, and cell-active LPCAT3 inhibitor €150.00
1432 (S)-(+)-Rolipram PDE4 inhibitor €115.00
4192 (S)-BI 2536 Dual PLK1/BRD4 bromodomain inhibitor €170.00
2296 (S)-Crizotinib MTH1 inhibitor €85.00
2718 (±)-Blebbistatin Potent and specific inhibitor of class II myosins €95.00
1687 (±)-E-Homocamptothecin Potent topoisomerase I (Topo 1) inhibitor €120.00
2786 (±)-PH 797804 Inhibitor of p38α MAPK €115.00
2537 1,5-Isoquinolinediol PARP1 inhibitor and neuroprotective agent €50.00
2434 1-Deazaadenosine Adenosine deaminase (ADA) inhibitor with cytostatic activity in vitro €140.00
1892 1-NM-PP1 Potent tyrosine kinase inhibitor (TKI) of multiple targets (Src, Fyn, Abl, CDK, Trk) €95.00
2989 15-LOX-1 inhibitor i472 Inhibitor of 15-lipoxygenase-1 (15-LOX-1) €170.00
4229 2',5'-Dideoxyadenosine P-Site inhibitor of adenylate cyclase €90.00
3565 2-FPBA First potent, reversible and slow-onset inhibitor of mandelate racemase (MR) €50.00
1496 3-Aminobenzamide Competitive small molecule inhibitor of PARP €40.00
2175 3PO Inhibitor of HIF-1-induced PFKFB3, an enzyme with a key role in glycolysis. €65.00
1902 4μ8C IRE1α inhibitor €105.00
3476 5-NIdR Potent inhibitor of translesion DNA synthesis (TLS) €120.00
1909 A 1070722 Selective inhibitor of GSK-3 €95.00
1666 A 357300 hydrochloride MetAP2 inhibitor €90.00
1831 A 66 PI3K inhibitor (p110-α specific) €95.00
1466 A 769662 AMPK activator €85.00
1698 A 770041 Orally active src-family selective lck inhibitor €140.00
2059 A 922500 Highly potent and selective diacylglycerol acyltransferase 1 (DGAT-1) inhibitor €105.00
2705 A-196 Potent and selective inhibitor of SUV4-20 €105.00

Items 1 to 30 of 1267 total

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Categories
  1. EC 1.4.3.4
  2. EC 2.7.12.2
  3. EC 3.4.23.46
  4. EC 2.7.11.26
  5. EC 3.1.4.53
  6. EC 2.7.11.21
  7. EC 2.7.11.1
  8. EC 2.7.1.2
  9. EC 2.7.10.2
  10. EC 2.7.10.1
  11. EC 4.1.1.32
  12. EC 5.2.1.8
  13. EC 3.1.4.17
  14. EC 1.17.3.2
  15. EC 3.4.24.65
  16. EC 1.1.1.21
  17. EC 3.1.4.3
  18. EC 3.4.14.10
  19. EC 2.7.11.22
  20. EC 2.1.1.37
  21. EC 2.4.2.30
  22. EC 3.4.21.37
  23. EC 3.4.24.24
  24. EC 2.4.2.12
  25. EC 2.7.1.153
  26. EC 2.7.11.24
  27. EC 3.4.22.56
  28. EC 3.4.21
  29. EC 2.7.11.13
  30. EC 3.1.1.7
  31. EC 3.4.23.16
  32. EC 2.7.11.31
  33. EC 2.5.1.10
  34. EC 2.3.1.48
  35. EC 3.4.24.86
  36. EC 4.2.1.1.
  37. EC 1.14.99.1
  38. EC 2.7.7.49
  39. EC 3.4.21.5
  40. EC 6.3.2.19
  41. EC 3.6
  42. EC 3.5.1.98
  43. EC 1.14.13.70
  44. EC 1.14.13.80
  45. EC 2.7.11.10
  46. EC 3.4.22.28
  47. EC 3.6.5.2
  48. EC 1.14.14.1
  49. EC 2.7.1.138
  50. EC 3.1.1.4
  51. EC 2.7.12.1
  52. EC 3.4.14.5
  53. EC 3.6.3.9
  54. EC 3.4.11.18
  55. EC 3.4.21.98
  56. EC 5.99.1.2
  57. EC 2.1.1.43
  58. EC 6.1.1.10
  59. EC 3.1.4.35
  60. EC 3.5.1.99
  61. EC 3.2.1.24
  62. EC 3.4.21.6
  63. EC 1.1.1.146
  64. EC 2.3.2.12
  65. EC 3.4.22.8
  66. EC 3.4.19.12
  67. EC 2.5.1.58
  68. EC 3.4
  69. EC 2.7.11.35
  70. EC 3.1.3.16
  71. EC 1.2.1.46
  72. EC 3.6.4.6
  73. EC 3.6.4.1
  74. EC 2.4.1.1
  75. EC 1.14.99.9
  76. EC 3.4.22.62
  77. EC 3.1.22.4
  78. EC 3.4.24
  79. EC 1.14.11.29
  80. EC 3.6.5.1
  81. EC 1.14.11
  82. EC 3.5.1.108
  83. EC 3.6.3.10
  84. EC 1.14.13.97
  85. EC 2.3.1
  86. EC 6.2.1
  87. EC 3.5.2.6
  88. EC 1.1.1.88
  89. EC 3.4.22
  90. EC 2.3.1.20
  91. EC 3.2.1.20
  92. EC 3.4.24.19
  93. EC 1.14.19.1
  94. EC 3.4.21.113
  95. EC 5.99.1.3
  96. EC 3.4.24.17
  97. EC 1.14.13.9
  98. EC 1.1.1.42
  99. EC 1.2.4.1
  100. EC 4.2.99.18
  101. EC 2.7.1.40
  102. EC 3.4.24.80
  103. EC 4.6.1.2
  104. EC 2.7.7.6
  105. EC 2.7.1.105
  106. EC 1.15.1.1
  107. EC 2.1.1.125
  108. EC 1.13.11.52
  109. EC 3.3.2.10
  110. EC 2.1.1.63
  111. EC 2.7.1.91
  112. EC 4.6.1.1
  113. EC 3.1.4.4
  114. EC 3.6.4.12
  115. EC 3.6.1.56
  116. EC 3.1.1.3
  117. EC 2.6.1.7
  118. EC 2.3.1.
  119. EC 3.3.2.6
  120. EC 5.3.99.3
  121. EC 3.1.3.67
  122. EC 2.7.11.4
  123. EC 3.5.3.1
  124. EC 2.7.11.25
  125. EC 1.3.3.1
  126. EC 3.6.1
  127. EC 1.13.11.31
  128. EC 1.3.5.1
  129. EC 2.7.1.20
  130. EC 3.6.4.4
  131. EC 3.6.5.6
  132. EC 1.13.12.7
  133. EC 1.2.1.36
  134. EC 3.5.4.4
  135. EC 3.1.1.23
  136. EC 2.5.1.18
  137. EC 1.1.1.27
  138. EC 2.7.11.17
  139. EC 2.3.3.8
  140. EC 6.5.1.1
  141. EC 1.14.11.2
  142. EC 1.4.3.21
  143. EC 1.10.2.2
  144. EC 1.1.1.95
  145. EC 1.1.98.3
  146. EC 3.2.1.85
  147. EC 2.7.11.1
  148. EC 3.1.2.22
  149. EC 1.1.1.1
  150. EC 3.1.3.48
  151. EC 2.7.4.9
  152. EC 4.2.1.1
  153. EC 4.4.1.1
  154. EC 2.7.1.137
  155. EC 3.6.3.8
  156. EC 3.4.21.68
  157. EC 3.4.14.1
  158. EC 2.7.1.67
  159. EC 1.1.1.51
  160. EC 2.7.11.12
  161. EC 2.1.1.45
  162. EC 3.1.1.13
  163. EC 3.1.6.2
  164. EC 1.14.13.39
  165. EC 3.4.21.26
  166. EC 1.6.5.11
  167. EC 1.14.13.48
  168. EC 3.2.2
  169. EC 2.7.11.20
  170. EC 1.6.3.1
  171. EC 2.3.1.26
  172. EC 2.3.1.50
  173. EC 3.4.23.45
  174. EC 3.1.3.1
  175. EC 2.7.7.7
  176. EC 1.5.1.5
  177. EC: 3.2.1.18
  178. EC 3.1.4
  179. EC 3.4.22.4
  180. EC 2.3.1.85
  181. EC 1.3.1.22
  182. EC 1.13.11.34
  183. EC 3.1.4.54
  184. EC 6.1.1.4
  185. EC 2.3.2.27
  186. EC 3.6.1.55
  187. EC 3.1.4.12
  188. EC 1.5.1.3
  189. EC 2.7.1.127
  190. EC 2.1.1.6
  191. EC 3.4.11
  192. EC 1.1.1.145
  193. EC 1.11.1.9
  194. EC 4.1.1.50
  195. EC 3.1.3.11
  196. EC 1.14.13.98
  197. EC 1.8.3.2
  198. EC 3.1.1.8
  199. EC 1.1.1.205
  200. EC 3.5.1.2
  201. EC 3.5.3.15
  202. EC 2.7.1.150
  203. EC 3.4.15.1
  204. EC 3.2.2.5
  205. EC 2.7.1.11
  206. EC 2.7.1.173
  207. EC 2.7.7.1
  208. EC 3.1.26
  209. EC 2.1.1.62
  210. EC 2.4.1.119
  211. EC 1.21.99.3
  212. EC 2.7.11-12
  213. EC 5.1.2.2
  214. EC 2.1.1.357
  215. EC 3.4.21.73
  216. EC 6.2.1.3
  217. EC 2.5.1.6
  218. EC 3.1.3.5
  219. EC 2.6.1.1
  220. EC 1.13.11.27
  221. EC 3.1.1.89
  222. EC 2.7.1.149
  223. EC 1.8.1.7
  224. EC:2.7.11.1
  225. EC 3.2.1.143
  226. EC 3.4.21.21
  227. EC 2.7.12.2
  228. EC 2.1.1.360
  229. EC 2.3.1.23
  230. EC 1.11.2.2
  231. EC 3.2.1.14
  232. EC 2.3.2.13
  233. EC 3.6.5.5
  234. EC 1.2.1.12
  235. EC 2.7.4.21
  236. EC 4.1.1.17
  237. EC 6.3.4.16
  238. EC 3.1.4.1
  239. EC 2.7.1.107
  240. EC 1.14.11.65
  241. EC 3.1
  242. EC 2.7.11.16
Filter by Endogenous Substrate
  1. (S)-Mandelate (1)
  2. (S)-Palmitoylated proteins (1)
  3. 2-Arachidonoyl glycerol (2-AG) (5)
  4. 3-Phosphoglycerate (2)
  5. 4-Hydroxyphenylpyruvate (1)
  6. Acetylcholine (5)
  7. Ack1-AR-ATM signaling (3)
  8. Adenosine (1)
  9. ADP (1)
  10. Aggrecan (1)
  11. AKT/GSK-3β/Snail signaling (1)
  12. Alcohol (5)
  13. Aldose (3)
  14. Ammonia; Urea (1)
  15. AMP (1)
  16. Amyloids (17)
  17. Angiotensin (2)
  18. AP2 (1)
  19. ATP (23)
  20. Atrial natriuretic peptide (ANP) (1)
  21. B-Cell Transformation (8)
  22. B-Cell transformation (4)
  23. BCAA (1)
  24. C-Nap1;PP1;Nek2 (1)
  25. cAMP (20)
  26. Carbondioxide (3)
  27. Catecholamines (2)
  28. Cation-Cl− cotransporters (CCCs) (1)
  29. Ceramide (1)
  30. cGMP (8)
  31. Chitin (2)
  32. Cholesterol (2)
  33. Choline-based esters (1)
  34. Coenzyme Q (CoQ) biosynthesis (1)
  35. Cortisone (2)
  36. Cyclic 2'3'- cGAMP (1)
  37. Cyclin dependent (CDK) (7)
  38. Cyclin Dependent (CDK) (19)
  39. Cytoskeleton (18)
  40. D-Luciferin (2)
  41. Decaprenylphosphoryl-beta-D-ribofuranose (DPR) (2)
  42. Dehydroepiandrosterone;Androstenedione (1)
  43. Deoxyuridine monophosphate (dUMP) (5)
  44. Diacylglycerol (4)
  45. Dihydrofolic acid (1)
  46. Dihydroorotate (2)
  47. DNA (2)
  48. DNA-damage response (5)
  49. DNA-RNA (137)
  50. dNTP (oxidized) (4)
  51. Eicosanoid epoxides (3)
  52. Endothelin;Non Selective (2)
  53. Farnesyl substrates (CaaX motif) (1)
  54. Fatty acid (Amides) (3)
  55. Fatty acid (Arachidonic acid) (22)
  56. Fatty acid (Linoleic acid) (1)
  57. Fatty acid (Stearic acid) (1)
  58. Fatty acids (3)
  59. Fructose 6-phosphate (4)
  60. G-Proteins (1)
  61. Geranyl Diphosphate (1)
  62. Gluconeogenesis (1)
  63. Glucose (4)
  64. Glucose Homeostasis (4)
  65. Glutamate oxaloacetate (1)
  66. Glutamine (3)
  67. Glutathion (GSH) (1)
  68. Glutathione disulfide,Thioredoxin (1)
  69. Glyceraldehyde 3-phosphate (1)
  70. Glycogen (1)
  71. Glycosides (6)
  72. GPCR-independent noncanonical G-protein signaling (1)
  73. GTP (20)
  74. Hedgehog (1)
  75. HER2 pathway;Rubicon (1)
  76. Histone (102)
  77. HMG-CoA (3)
  78. Hydrogen peroxide,Chloride (1)
  79. Hypoxanthine (2)
  80. Hypoxia-signaling cascade (8)
  81. Inosine monophosphate (IMP) (2)
  82. Inositol hexakisphosphate (InsP6) (1)
  83. Inositol-1,4,5-trisphosphate (InsP3) (2)
  84. Interleukin (3)
  85. Isocitrate (6)
  86. IκB (9)
  87. JAK-STAT Pathway (23)
  88. Kinins (3)
  89. L-Arginine (4)
  90. L-Cysteine (1)
  91. L-Kynurenine (10)
  92. Lactate (2)
  93. Lands cycle (1)
  94. LCCs;RyRs;PLB (3)
  95. Lipid A precursor (3)
  96. LPC (4)
  97. Mannosidose (α form) (1)
  98. MAPK (64)
  99. MEK (17)
  100. Methionine (1)
  101. Microtubules (4)
  102. Mono-amines (12)
  103. NADH (3)
  104. NADP+ (1)
  105. NADPH (2)
  106. NEDD8 (1)
  107. Neryl Diphosphate (1)
  108. NF-κB pathway (1)
  109. NF-κB Pathway (4)
  110. Nicotinamide D-ribonucleotide (6)
  111. Nicotinamide riboside kinase (1)
  112. NMNAT (1)
  113. Non Selective (28)
  114. Non Selective (ADF-cofilin) (4)
  115. Non Selective (Arginine Sites Proteins) (10)
  116. Non Selective (Arginine sites proteins) (5)
  117. Non Selective (Aspartate Peptide Bonds) (6)
  118. Non Selective (CHK2,p53) (2)
  119. Non Selective (CHK2; p53) (8)
  120. Non Selective (CHK2;p53) (1)
  121. Non Selective (COX substrates; Cannabinoids) (1)
  122. Non Selective (Cysteine Peptide Bonds) (4)
  123. Non Selective (Cysteine Peptide Bonds); Dopamine; Adrenaline, (Nor-) (1)
  124. Non Selective (Glucocorticoid) (2)
  125. Non Selective (Histone; Survivin; Topo) (3)
  126. Non Selective (Histone; Survivin; Topo; TPX2) (5)
  127. Non Selective (Histone; Survivin; Topo; TPX2); JAK-STAT Pathway; Non Selective (Phosphorylation Substrates) (1)
  128. Non Selective (LIM; p53; TPX2) (5)
  129. Non Selective (LIM;p53;TPX2) (3)
  130. Non Selective (Lysine Sites Proteins) (1)
  131. Non Selective (Methionine Peptide Bonds) (1)
  132. Non Selective (Mitotic spindle checkpoint) (1)
  133. Non Selective (Mitotic Spindle Checkpoint) (4)
  134. Non Selective (Phosphorylation substrates) (18)
  135. Non Selective (Phosphorylation Substrates) (91)
  136. Non Selective (Proline Peptide Bonds) (9)
  137. Non Selective (Ribosomal proteins) (9)
  138. Non Selective (Serine Peptide Bonds) (14)
  139. Non Selective (Serine peptide bonds) (5)
  140. Non Selective (Serine-Threonine and Tyrosine Specific Phosphodiesters) (9)
  141. Non Selective (Serine-Threonine;Tyrosine Specific Phosphodiesters) (1)
  142. Non Selective (Thiols) (1)
  143. Non Selective (Tripeptides) (1)
  144. Non Selective (Tyrosine specific phosphomonoesters) (5)
  145. Non Selective (Tyrosine Specific Phosphomonoesters) (14)
  146. Non Selective (Ubiquitin peptides) (38)
  147. Oligosaccharide (1)
  148. Ornithine (1)
  149. p53 (16)
  150. Palmitoyl-CoA; L-serine (1)
  151. Peptides (Endoplasmatic reticulum) (1)
  152. Phosphatidylcholine (2)
  153. Phosphatidylinositol (98)
  154. Phosphatidylinositol 5-phosphate (PI-5-P) (1)
  155. Phospholipid metabolism (1)
  156. Phospholipids (5)
  157. phosphorylated Ampk α (pAmpkα) (1)
  158. Plasminogen (1)
  159. Prostaglandins (1)
  160. Protein degradation (7)
  161. Protein Disulfide Isomerase (PDI) (1)
  162. Protein L-arginine (1)
  163. Protein Rad21 (1)
  164. Pyruvate (3)
  165. Quinol (1)
  166. S-adenosylmethionine (1)
  167. S-nitrosoglutathione (1)
  168. S-palmitoylated proteins (1)
  169. Securin,B type cyclins (1)
  170. Serpin (9)
  171. Smad (3)
  172. Sonic Hedgehog (2)
  173. Sphingolipid (2)
  174. Sphingosine (5)
  175. Steroid (Androgens) (3)
  176. Steroid (Lanosterol 14-α) (5)
  177. Steroids (2)
  178. Succinic acid (1)
  179. Superoxide (1)
  180. T-Cell signaling (1)
  181. T3 (1)
  182. Thymidylate pathway (1)
  183. TNF-α (1)
  184. Triglycerides (4)
  185. Unfolded Protein Response (EIF2 Selective) (3)
  186. Unfolded protein response (EIF2 selective) (1)
  187. Unfolded Protein Response (Non Selective) (10)
  188. Unfolded protein response (Non selective) (2)
  189. Wnt proteins (3)
  190. Xanthine (1)
  191. β-Lactams (3)
Filter by Action
  1. Activator (31)
  2. Antagonist (1)
  3. Degrader (5)
  4. Degrader;Inhibitor (1)
  5. Disruptor (1)
  6. Inducer (3)
  7. Inhibitor (1206)
  8. inhibitor (2)
  9. Ligand (1)
  10. Mimic (1)
  11. Modulator (3)
  12. PAM (1)
  13. Poison (1)
  14. Precursor (2)
  15. Stimulator (4)
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