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Verapamil hydrochloride
- Parent CAS: 52-53-9
- Soluble in water, DMSO and EtOH
- MF: C27H38N2O4.HCl
- MW: 491.06
Description
Verapamil hydrochloride is a calcium antagonist which inhibits the slow inward current of calcium in normal cardiac tissues, and in the atrioventricular and sinoatrial nodes.
More Information
| Parent CAS No. | 52-53-9 |
|---|---|
| Chemical Name | 5-((3,4-Dimethoxyphenethyl)(methyl)amino)-2-(3,4-dimethoxyphenyl)-2-isopropylpentanenitrile hydrochloride |
| SMILES | C1(OC)C(OC)=CC(C(CCCN(C)CCC2C=C(OC)C(OC)=CC=2)(C(C)C)C#N)=CC=1.Cl |
| MFCD | MFCD00055208 |
| InChi | InChI=1S/C27H38N2O4.ClH/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6;/h9-12,17-18,20H,8,13-16H2,1-7H3;1H |
| InChiKey | DOQPXTMNIUCOSY-UHFFFAOYSA-N |
| CID | 62969 |
| Short Description | Ca channel antagonist |
References
- RN Brogden et al. Verapamil: a review of its pharmacological properties and therapeutic use in coronary artery disease. Drugs. 1996 May;51(5):792-819.
- D McTavish et al. Verapamil. An updated review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in hypertension. Drugs. 1989 Jul;38(1):19-76.
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