E7449 mesylate - 2X-121

Based on 8 reference(s) in Google Scholar 8 10 8

Axon 3398

CAS [1140965-47-4]

MF C18H15N5O.CH4O3S
MW 413.45

  • Purity: 98%
  • Soluble in water and DMSO
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E7449 mesylate

Description

E7449 mesylate is a potent, brain penetrable and orally bioavailable dual inhibitor of PARP1/2 and tankyrase1/2, which inhibits growth of DNA repair deficient tumors and antagonizes Wnt signalling. E7449 mesylate exhibits IC50 values of 2.0 and 1.0 nM for PARP1 and PARP2, respectively.

KEYWORDS: E7449 mesylate | Supplier | PARP1/2-TNKS1/2 inhibitor | 2X-121 | E 7449 mesylate | E-7449 mesylate | CAS [1140965-47-4] | [1140964-99-3] | DNA-RNA | PARP | TNKS | Inhibitor | Enzymes

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5 mg €110.00 In Stock
25 mg €390.00 In Stock
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2 x 5 mg €180.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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