Bulk Inquiry
NU 1025
- Soluble in 0.1N NaOH(aq) and DMSO
- MF: C9H8N2O2
- MW: 176.17
Description
More Information
| Parent CAS No. | 90417-38-2 |
|---|---|
| Chemical Name | 8-Hydroxy-2-methyl-3H-quinazolin-4-one |
| SMILES | C1C=C2C(=O)NC(C)=NC2=C(O)C=1 |
| MFCD | MFCD00942555 |
| InChi | InChI=1S/C9H8N2O2/c1-5-10-8-6(9(13)11-5)3-2-4-7(8)12/h2-4,12H,1H3,(H,10,11,13) |
| InChiKey | YJDAOHJWLUNFLX-UHFFFAOYSA-N |
| CID | 135398517 |
| Short Description | PARP inhibitor |
References
- R Kaundal et al. Neuroprotective effects of NU1025, a PARP inhibitor in cerebral ischemia are mediated through reduction in NAD depletion and DNA fragmentation. Life Sciences 2006, 79(24), 2293-302.
- KJ Bowman et al. Potentiation of anti-cancer agent cytotoxicity by the potent poly(ADP-ribose) polymerase inhibitors NU1025 and NU1064. Br. J. Cancer. 1998, 78 1269.
- CA Delaney et al. Potentiation of temozolomide and topotecan growth inhibition and cytotoxicity by novel poly(adenosine diphosphoribose) polymerase inhibitors in a panel of human tumor cell lines. Clin. Cancer Res. 2000, 6, 2860.
Related Products
| AXON ID | NAME | FROM PRICE |
|---|---|---|
| 1268 | DR 2313 |
From $99.00 |
| 1464 | Olaparib |
From $55.00 |
| 1496 | 3-Aminobenzamide |
From $44.00 |
| 1529 | AG 014699 |
From $66.00 |
| 1566 | Iniparib |
From $66.00 |
| 1593 | Veliparib |
From $44.00 |
| 2001 | KU-0058948 hydrochloride |
From $148.50 |
| 2241 | AZD2461 |
From $104.50 |
| 2369 | UPF 1069 |
From $82.50 |
| 2502 | Talazoparib |
From $99.00 |
| 2759 | ME0328 |
From $104.50 |
| 2885 | GeA-69 |
From $104.50 |
| 2888 | Veliparib dihydrochloride |
From $99.00 |
| 2928 | Niraparib |
From $99.00 |
| 3113 | Rucaparib camsylate |
From $99.00 |
| 3398 | E7449 mesylate |
From $121.00 |
| 4179 | KU-0058948 |
From $148.50 |
| 4276 | AG14361 |
From $143.00 |
| 4435 | RBN-2397 |
From $198.00 |
