Otilonium bromide

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 3158

CAS [26095-59-0]

MF C29H43BrN2O4
MW 563.57

  • Purity: 99%
  • Soluble in DMSO

Otilonium bromide


Otilonium bromide is a Ca2+ channel blocker. The main action consists in the blockade of Ca2+ entry through L-type Ca2+ channels and interference with intracytoplasmatic Ca2+ mobilization necessary for smooth muscle cell (SMC) contraction, thus preventing excessive bowel contractions and abdominal cramps. Further, Otilonium bromide blocks the T-type Ca2+ channels and interferes with the muscarinic responses; it interacts, directly or indirectly, with the tachykinin receptors on SMC and on primary afferent neurons whose combined effects may result in the reduction of motility and abdominal pain.

KEYWORDS: Otilonium bromide | supplier | Ca channel blocker | CAS [26095-59-0] | [105360-89-2] | Calcium | Non Selective | Blocker | Ion Channels | Spasmolytic | IBS | Irritable Bowel Syndrome

Size Unit Price Stock
10 mg €70.00 In Stock
50 mg €170.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

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